Physiologic Tailoring of Treatment in Resistant Hypertension

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Physiologic Tailoring of Treatment in Resistant Hypertension

Resistant hypertension is a major opportunity for prevention of cardiovascular disease. Despite widespread dissemination of consensus guidelines, most patients are uncontrolled with approaches that assume that all patients are the same. Causes of resistant hypertension include 1) non-compliance 2) consumption of substances that aggravate hypertension (such as salt, alcohol, nonsteroidal anti-in...

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Diuretic treatment of resistant hypertension.

In patients with hypertension resistant to three or four drugs including a thiazide diuretic substitution of frusemide for the thiazide, or the addition of spironolactone, produced significant reductions in blood pressure and body weight. The response did not depend on the presence of overt fluid retention, renal impairment, or the use of antihypertensive drugs of high potency. Women had larger...

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Clinical approach in treatment of resistant hypertension

Resistant hypertension, defined as failure to achieve target blood pressure despite the use of optimal or maximum doses of at least 3 agents, one of which is a diuretic, or requiring 4 or more medications to achieve blood pressure goal, is likely to affect up to 20% of all patients with hypertension. Apparent resistant hypertension may be caused by medication nonadherence, substances that eithe...

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Treatment: special conditions: resistant hypertension.

One of the most common reasons that physicians and other health care providers refer a patient to a hypertension specialist is because that patient’s blood pressure (BP) is not at goal. The term that has become most commonly used now to classify and define these patients is ‘‘resistant hypertension,’’ but some still refer to these patients as having refractory hypertension. A resistant hyperten...

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Novel strategies for treatment of resistant hypertension

Resistant hypertension, defined as blood pressure (BP) remaining above goal despite the use of 3 or more antihypertensive medications at maximally tolerated doses (one ideally being a diuretic) or BP that requires 4 or more agents to achieve control, occurs in a substantial proportion (>10%) of treated hypertensive patients. Refractory hypertension is a recently described subset of resistant hy...

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ژورنال

عنوان ژورنال: Current Cardiology Reviews

سال: 2010

ISSN: 1573-403X

DOI: 10.2174/157340310791162695